Cognition, balance, and retina manifestations in Long COVID: A case–control study

Long COVID is a multisystemic condition that complicates diagnosis due to the nonspecific and heterogeneous nature of its symptoms. The most frequently reported symptoms are fatigue, brain fog, cognitive impairment, insomnia, dizziness, and vertigo. Some symptoms may persist for years, and it is unclear whether they will become permanent. Long COVID substantially impacts affected individuals…

“Mild Traumatic Brain Injury: Overlooked Rehabilitation Care Pathways”: an innovative initiative in XXX region to promote patient recovery

Mild traumatic brain injury (mTBI) represents a public health challenge in terms of number of patients, of which 15–20% suffer persistent long-term symptoms, affecting resumption of daily activities. Authorized under Article 51 of the 2018 Social Security Financing Act, the pilot program “Mild traumatic brain injury: overlooked rehabilitation care pathways” began in March 2023.Very early…

Resiliency in Care: A Family Medicine Case of Adult Autism Spectrum Disorder in a Rural Community

Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental condition that is often under-recognized and misdiagnosed in primary care, particularly in low- and middle-income countries. Adult presentations of ASD remain uncommon in family medicine literature, despite their significant clinical, psychosocial, and caregiver implications. The challenges are magnified in resource-limited rural settings where access to specialist services…

The influence of inflammatory and fibrotic markers on atrial fibrillation development in patients with arterial hypertension

Arterial hypertension (AH) and atrial fibrillation (AF) are highly prevalent cardiovascular disorders that frequently coexist and represent major public health challenges. AH substantially increases the risk of AF and plays a pivotal role in atrial remodeling; however, the underlying pathophysiological mechanisms remain only partially understood.To evaluate the association between arterial stiffness (AS) and selected inflammatory…

Chronic Kidney Disease: a proposal for inteìgrated management between Primary Care and Hospital Nephrology

Chronic Kidney Disease (CKD) represents one of the most significant global health challenges, with high prevalence in the adult population and with strong clinical, economic, and social impact. CKD is characterized by a progressive decline in renal function to end-stage kidney disease requiring renal replacement therapy, and is associated with reduced quality of life, increased…

Suspected Digoxin Toxicity Due to Polypharmacy in an Older Adult: A Case Report from Primary Care

Older adults are at increased risk of adverse drug reactions due to multimorbidity, polypharmacy, and age-related changes in pharmacokinetics and pharmacodynamics. Medications with a narrow therapeutic index, such as digoxin, pose a particular challenge in primary care. Reduced renal clearance, dehydration, incorrect dosing, and drug–drug interactions may precipitate digoxin toxicity, which often presents with nonspecific…

”Breathing Hope” Holistic Care for a Child with Probable Hurler Syndrome with Recurrent Pneumonia

Hurler Syndrome is a rare lysosomal storage disorder with progressive multisystem involvement. Respiratory complications, particularly recurrent pneumonia, are a major cause of morbidity in affected children. These complications are often magnified in low socioeconomic settings where access to healthcare resources, preventive services, and continuity of care are limited. This family case highlights the interaction of…

A 12-week Randomized Double-Blind Clinical Trial, Evaluating the Effect of Lithospermum erythrorhizon (Gromwell) Root Extract on Skeletal Muscle Function in Adults over 50 Years of Age

Lithospermum erythrorhizon (gromwell) root contains shikonin derivatives with anti-inflammatory and antioxidant properties, and preclinical studies have suggested protective effects on muscle tissue. However, clinical evidence in humans remains limited. Given that age-related loss of muscle strength contributes significantly to functional decline in older adults, effective and safe nutritional interventions are needed.This study aimed to evaluate…