From screen to clinic: translating longevity protocols to primary care

A popular documentary series presents experimental “Medicine 3.0” longevity protocols (e.g., genetic risk awareness, thermal stress, fasting, functional training) framed as strategies to extend healthspan. The question for family medicine is how to translate such content into feasible, equitable, evidence-informed preventive care.To classify the documentary’s featured interventions; appraise feasibility, safety considerations, and equity risks for…

Preliminary evaluation of biotinidase deficiency screening results in Igdir province: an ongoing retrospective analysis

Biotinidase deficiency (BD) is an autosomal recessive metabolic disorder that can lead to severe neurological and cutaneous symptoms if untreated. Early detection through neonatal screening is vital for preventing irreversible complications. Given the high rates of consanguineous marriages in certain regions of Türkiye, local data are essential for assessing regional prevalence within the National Newborn…

Knowledge, Attitude and practices on Antibiotic use among HealthCare Professionals in Pakistan

Antibiotic use to combat infections is common everwhere; however, antimicrobial resistance (due to indiscriminate use of antibiotics) has become a global challenge. The World Health Organization (WHO) has declared antimicrobial resistance among the top 10 global public health challenges to mankind.  Healthcare professionals are actively involved in the process of prescribing, dispensing and administering antibiotics.Antibiotics are extensively dispensed…

Caring Without Collapse: Karoshi in General Practice

Karoshi, a Japanese term meaning “death due to overwork,” describes fatal physical and psychological consequences associated with chronic occupational stress, excessive workload, and burnout. While traditionally recognised in corporate settings, the concept is increasingly relevant to General Practice. Rising consultation demand, workforce shortages, administrative burden, and emotional labour place family physicians at growing risk. Understanding…

Beyond the acute abdomen: A primary care case of ovarian torsion revealing familial cystic kidney disease

Acute abdominal pain in adolescent females is a common but high-risk presentation in primary care. Gynecological emergencies such as ovarian torsion require rapid recognition and urgent referral to prevent loss of ovarian function. Additionally, incidental findings during acute evaluation may uncover previously unrecognized hereditary conditions. This case highlights the critical gatekeeping role of family physicians…

Transient Ischemic Attack after Anticoagulant Discontinuation in Atrial Fibrillation

Atrial fibrillation (AF) is common in older adults and is strongly associated with ischemic stroke and transient ischemic attack (TIA). Anticoagulant therapy is essential for stroke prevention; however, long-term adherence is often suboptimal. In primary care, unrecognised treatment discontinuation may expose patients to avoidable cerebrovascular risk.A 76-year-old woman presented to primary care with sudden numbness…

Transforming Long-Term Condition Management Through Digital and AI-Enabled Recall: A Practical Framework for Global Primary Care

Long-term conditions (LTCs) are the largest driver of primary care workload globally. As populations age and multimorbidity rises, traditional manual recall systems can no longer keep pace. Many health systems face the same structural pressures: rising demand, increasing emergency presentations, and limited workforce capacity. AI-enabled recall offers a practical, scalable and evidence-based way to modernise…

The Boundaries Prescription: Treating Co-Dependency in General Practice

Co-dependency subtly permeates everyday relationships, presenting as normal dynamics as a ‘giver’ and ‘taker’, between doctor/patient, parent/child, spouses, etc. While healthy interdependence is essential, difficulties arise when these patterns become habitual cycles of overgiving and rescuing. In General Practice, co-dependency is frequently overlooked, causing clinician burnout, compassion fatigue, blurred boundaries, and patient overdependence. It may also…