Lipschütz ulcers as the first manifestation of infectious Mononucleosis

Lipschütz genital ulcers are a rare condition affecting young women, usually caused by viral infections, most often Epstein-Barr virus (EBV). They pose a diagnostic challenge since they do not fall into the main causative categories such as sexually transmitted infections (STIs) or autoimmune processes.A healthy 25-year-old woman presented to her Family Doctor after urgent evaluation by…

Narrative review, methods for creating and developing a prevention intervention for runners to improve the relevance and safety of dietary supplement use

The dietary supplement (DS) market is booming, as is the world of sports, particularly running. These trends are intertwined, with athletes consuming more and more DS to enhance their performance. DS are not regulated products, and their composition remains unreliable, with a particular risk of contamination by doping substances. Furthermore, patients, who are the primary…

How Food Insecurity Influences Exercise and Eating: The Roles of Muscle Dysmorphia and Resilience

Food insecurity (FI) is linked to adverse physical and psychological health outcomes, including increased risks of addictive behaviors and eating disorders. Emerging evidence indicates that FI may increase vulnerability to muscle dysmorphia (MD), defined as obsessive preoccupation with muscularity and leanness. However, the mechanisms through which FI influences exercise and eating-related psychopathology remain insufficiently clarified.This…

Audit; Sick Day Rule advice in patient’s prescribed SGLT2 inhibitors.

Sick day rules are critical guidelines that help patients manage their prescribed medications safely during periods of acute illness, such as vomiting, or dehydration. These rules are especially important for individuals with chronic conditions. Failure to adjust or withhold certain medications during illnesses can lead to serious complications, including hypoglycaemia, or hypotension. Despite their importance,…

HbA1C : its limitations and alternatives

HbA1C is the mainly used biomarker in the glycemic monitoring in diabetic patients. The dosage may be altered in some clinical situations such as hemoglobinopathies, hemolysis, chronic renal failure (CRF), splenomegaly, hereditary spherocytosis or even pregnancy, leading clinicians to question its reliability. Glycated albumin (GA), Fructosamine (FA) and continuous glucose monitoring (CGM) devices are presented…

Retrospective study of Cardiac Amyloidosis (AC), Red Flags, Cardiorenal syndrome [Chronic Kidney Disease (MRC)-Heart Failure (HF), and BUN/creatinine ratio (UCR).

In the DIAMOND study (in Italy), the epidemiological data on AC derive from real-world studies conducted on large populations attending cardiology clinics. The red flags are very varied in the pathology and do not guide the diagnosisTo evaluate naive subjects for cardiac amyloidosis through red flags and laboratory and instrumental investigations15 General Practitioners participated in…

The contribution of a special Diabetes and Lipids Primary Care Unit to the secondary prevention of ischemic stroke in diabetic patients

Secondary stroke prevention can reduce the risk of recurrent stroke by 90%. Special primary care units enhance the prospect of secondary prevention in diabetics. To assess the contribution of our diabetes- lipid unit to the secondary stroke prevention in diabetics with a first-ever ischemic stroke two years after the event. All the patients included in…

Dapagliflozin Eligibility and Renal Testing Gaps in Chronic Kidney Disease: A Retrospective Cross-Sectional Analysis in Primary Care

Chronic kidney disease (CKD) substantially increases cardiovascular morbidity, risk of renal failure, and premature mortality. UK guidelines NICE TA775 (2022) recommends dapagliflozin for patients with CKD (eGFR 25-75 mL/min/1.73m²) on optimised ACEi/ARB therapy who also have type 2 diabetes or significant albuminuria (ACR ≥22.6 mg/mmol). Large clinical trials have demonstrated the reno- and cardioprotective benefits…