Cancer Risk Reduction Associated with Ezetimibe–Statin Combination Therapy in Primary Care

Dyslipidemia is one of the most common chronic conditions managed in primary care, and long-term preventive strategies are essential to reduce both cardiovascular and cancer-related morbidity. While statins are widely used, the potential broader benefits of adding ezetimibe—particularly regarding cancer prevention—remain unclear in routine practice. As combination therapy is increasingly initiated in primary care settings,…

Exercise-Induced Vasculitis (“Disney Rash”)

Introduction: Exercise-induced vasculitis, often referred to as “Disney rash,” is a benign cutaneous small-vessel vasculitis that develops on the lower extremities after sustained physical exertion, particularly in hot or humid conditions. Although the rash may appear striking—with erythematous or purpuric, bruise-like patches—it is not dangerous and does not lead to long-term complications. The underlying mechanism…

Who are the patients consulting general practitioners in the municipal health centers of the city of XXX (Paris area), and where do they come from?

Territorial health inequalities tend to worsen with the scarcity of medical provision. This scarcity varies across territories, whereas access to care should be as open as possible, especially in General Practice (GP), the entry point into the healthcare pathway. The city of XXX (Paris area) is particularly affected by this phenomenon, while its economically disadvantaged…

Migraine Revisited: New Frontiers in Primary Care

Migraine is a leading cause of disability and a frequent presentation in primary care, where traditional preventives such as topiramate and propranolol remain widely used despite tolerability issues and limited adherence. Advances in migraine science have introduced calcitonin gene–related peptide (CGRP)–targeted therapies, including the oral CGRP receptor antagonist atogepant. These emerging treatments offer improved safety…

Detection of occupational respiratory disease in primary health care – a case report

Hypersensitivity pneumonitis (HP) is an immune-mediated interstitial lung disease triggered by repeated inhalation of organic or inorganic antigens in susceptible individuals. Its heterogeneous and often nonspecific clinical presentation contributes to diagnostic delay, which may lead to progression toward irreversible pulmonary fibrosis. This case report describes a 51-year-old factory worker involved in toy-painting, who developed non-fibrotic…

Enhancing Primary Care research through AI tools: from literature to publication update

Artificial Intelligence (AI) has rapidly evolved into an essential component of contemporary medical research, offering increasingly robust capabilities to support evidence retrieval, synthesis, analysis, and scientific communication. Primary care professionals—often constrained by limited time and research support—stand to benefit substantially from AI-driven tools that streamline key stages of the research workflow.Demonstrate how current-generation AI tools…

Updating of a Knowledge Agenda using an innovative online methodology directly involving General Practitioners combined with a invitational conference

Since the first Knowledge Agenda was published, new challenges and gaps have emerged, creating the need for an updated agenda. To ensure future research meets the knowledge needs of general practitioners, the Dutch College of General Practitioners (NHG) has systematically revised the agenda in close collaboration with GPs.Its goal is to strengthen and support general…

Chest pain and fever: It’s not always myopericarditis

A 54-year-old patient with fever treated in primary care and subsequently in an emergency department.54-year-old patient with history of hypertension treated with ramipril 10 mg/day. Smokes 20 cigarettes per day. Patient visits the emergency department with a fever of 38 degrees. He explains that four days earlier he experienced chest pain radiating to his back…

Home Monitoring in Primary Care for CVRM Patients

Cardiovascular diseases (CVD) are a major cause of morbidity and mortality. In Dutch primary care, patients with elevated cardiovascular risk are monitored through the CVRM program. Increasing workload and staff shortages in general practice threaten structured monitoring. Home monitoring may support care, but home monitoring remotely supervised by a Medical Control Center (MRC) has not…

CBT in primary care: empowering physicians to drive mental and behavioral health change

CBT plays a vital role in mental health care within primary care settings. •CBT encompasses a group of approaches that focus on identifying and changing negative thought patterns and behaviors.  •These approaches include cognitive therapy, which focuses on identifying and modifying distorted thought patterns;  •Dialectical behavior therapy (DBT), which addresses destructive thoughts and behaviors •Mindfulness…