When chest pain is not cardiac: Herpes zoster revealed by careful inspection in family medicine – A practice-based reflection
Ilksen Yazgulu SENOL, Alperen KUCUKUYSAL and Vildan MEVSIM
Chest pain is a common reason for emergency department visits, where the primary clinical priority is the exclusion of acute coronary syndrome. Although this approach is appropriate and lifesaving, non-cardiac causes—particularly dermatological and neurological conditions—may be overlooked during rapid, protocol-driven assessments. In contrast, primary care settings allow more comprehensive physical examination and diagnostic integration. This case illustrates how careful inspection in family medicine led to the correct diagnosis after repeated negative cardiac evaluations.A 58-year-old woman presented repeatedly to the emergency department with left-sided thoracic pain radiating from the back toward the chest wall. Serial high-sensitivity troponin measurements and repeated electrocardiograms showed no evidence of acute coronary syndrome. Despite reassurance, her pain persisted. The patient subsequently consulted a family medicine clinic. After detailed history-taking, a full physical examination was performed, including complete inspection of the upper body after removal of clothing. A clustered vesicular rash on an erythematous base, approximately 5 cm in diameter, was observed on the left lateral thorax at the level of the seventh rib, extending toward the posterior axillary line. The distribution of pain corresponded to the same dermatome. Based on these findings, a diagnosis of herpes zoster was established, and antiviral treatment was initiated.This case highlights the diagnostic value of simple inspection in patients presenting with chest and back pain. It demonstrates how non-cardiac causes may be missed when physical examination is incomplete, despite extensive cardiac investigations.Time pressure and task-focused workflows in emergency settings may limit thorough inspection, particularly of posterior body regions. In primary care, continuity and adequate consultation time enable complete examination and broader differential diagnosis. Emphasizing inspection in patients with unexplained chest or back pain may reduce unnecessary investigations and diagnostic delays.Patients with herpes zoster may present with back or chest pain, which can mimic cardiac pain. Posterior localization of lesions may hinder detection during rapid emergency assessments. This case illustrates the difference between emergency and primary care approaches.Careful physical inspection remains a cornerstone of clinical diagnosis. A comprehensive primary care approach can reveal conditions overlooked in acute care settings, ensuring timely treatment and avoiding unnecessary diagnostic procedures.
