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Pediatric Chest Pain: A Literature Review for Primary Care

Zhanna OLCHOV, Andreia LOBO, Snežana KNEŽEVIĆ, Ozden GOKDEMIR and Gokce ISCAN

Chest pain is a common presenting complaint among children and adolescents and accounts for a significant number of visits to Primary Care and Emergency departments. Despite its alarming nature for patients and families, pediatric chest pain is most often benign, frequently resulting in school absences, activity limitations, and heightened anxiety. A structured and informed approach in Primary Care can reduce unnecessary healthcare utilization and improve family reassurance.This literature review aims to summarize the current evidence on pediatric chest pain, focusing on epidemiology, common etiologies, and the role of the Family Doctor in clinical evaluation, diagnosis, and management.A literature review was conducted using UpToDate and PubMed, focusing on publications from 2011 and 2012. The MeSH terms “chest pain” and “children” were applied to identify relevant studies addressing causes, frequency, and diagnostic approaches.In pediatric populations, chest pain is overwhelmingly benign, with only about 10% of cases associated with underlying organic disease. Musculoskeletal causes are the most common, while cardiac etiologies are rare even in chronic presentations. Chronic symptoms may recur every two weeks and persist for years without cardiac involvement. In the majority of cases, a thorough history and targeted physical examination provide sufficient diagnostic clarity. When the physical exam is normal or consistent with musculoskeletal origin, further diagnostic testing is generally unnecessary.Although the symptom often raises concern for serious disease—particularly cardiac pathology—the evidence indicates that most cases can be safely evaluated and managed in Primary Care. A holistic approach that includes family context, psychosocial contributors, and reassurance is central to reducing anxiety and preventing unnecessary referrals or investigations.Pediatric chest pain is rarely cardiac in origin and can be effectively assessed by Primary Care clinicians through thorough history-taking and physical examination. Early recognition of benign patterns and appropriate reassurance support improved quality of life for patients and families while preventing overuse of healthcare services.   Keywords: Chest Pain, Child, Adolescent