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Non-specific back pain and a normal X-ray: using VAS and clinical judgement to detect hidden malignancy in Primary Care

Yang LUO, Tan HUI JUAN JENNIFER, Lee SHAOWEN JOSHUA and Tan KOK HENG ADRIAN

Back pain is one of the most common presentations in primary care. Distinguishing benign musculoskeletal causes from serious pathology presents a huge diagnostic challenge. This can be compounded by language barriers. This case demonstrates how GPs can use the tools at their disposal, namely the visual analogue scale (VAS), strong clinical suspicion, and critical analysis of inconsistent findings, to diagnose the most obscure of cases.A 58-year-old man presented to the GP with non-specific lower back pain. The consultation was complicated by a language barrier, with the son translating, limiting the reliability of the history. The neurological and spinal examination was normal; however, blood tests revealed normocytic anaemia and an isolated elevated ALP. Despite a normal lumbar X-ray, the patient reported disproportionate pain reflected by his high VAS score. This inconsistency, combined with the anaemia, triggered the GP’s clinical curiosity, who referred the patient via a 2-week haematological malignancy pathway. The MRI revealed extensive spinal metastases secondary to stage IV prostate cancer. It was due to the GP’s clinical suspicion, combined with his critical analysis of non-specific investigations, that led to this diagnosis.Although prostate cancer is well documented, very rarely does it present solely as back pain, without urinary, neurological or red flag symptoms. The uniqueness of this case lies in how the initial imaging appeared normal. Nonetheless, the diagnostic pathway was instead spearheaded by clinical intuition, biochemical abnormalities, and a mismatch between symptoms and objective findings. Few cases highlight the value of VAS scoring in discriminating malignant differentials or the impact of language barriers in masking underlying pathology.This case underscores the importance of early interpreter involvement to prevent diagnostic blind spots. It reinforces that a clinician’s mind, along with baseline blood tests, is a powerful diagnostic tool. GPs should always remain curious, especially when imaging and symptoms do not align. In the future, artificial intelligence in imaging can be utilised to minimise diagnostic errors and identify subtle metastases.This case illustrates the crucial role of GPs’ clinical suspicion and holistic assessment in identifying serious diseases hidden within routine presentations.