Violence against women (VAW) remains a major public health and human rights concern in Brazil. The COVID-19 pandemic intensified social stressors, potentially modifying patterns of domestic violence. Understanding these trends is essential for strengthening primary care responses and informing international public health policy.To compare femicide rates and national hotline reports of VAW during the pandemic (2020–2022) and post-pandemic (2023–2025) periods, and to assess whether differences were statistically significant.A retrospective analysis of government datasets was conducted using femicide counts from national security records and Ligue 180 hotline reports. Data were grouped into two periods: pandemic (2020–2022) and post-pandemic (2023–2025). Mean values were compared using independent samples T-tests, with statistical significance defined as p<0.05. Partial 2025 data were proportionally adjusted. Percentage changes were calculated to evaluate relative variation between periods.The mean number of femicides increased from 1,388/year during the pandemic to 1,452/year post-pandemic, representing a 4.6% rise, although this difference was not statistically significant (p = 0.18). Hotline reports showed a marked increase, rising from 89,233/year to 110,911/year, corresponding to a 24.3% increase, which was statistically significant (p = 0.03). Between 2020 and 2024, femicides increased modestly (1,355 → 1,459), while hotline reports grew substantially (82,991 → 132,084), suggesting more frequent reporting of non-lethal forms of violence.The data indicate that lethal violence against women remained relatively stable across the pandemic and post-pandemic periods, while reporting of non-lethal violence increased significantly after the pandemic. This divergence may reflect increased awareness, improved access to reporting mechanisms, or heightened incidence driven by socioeconomic pressures. Primary care settings—often the first point of contact for women experiencing violence—must adapt to this rising demand by strengthening screening, training, and integrated referral pathways. Moreover, Brazil’s experience may inform international strategies, particularly in regions facing similar post-pandemic social vulnerabilities. Limitations include potential underreporting, changes in classification practices, and reliance on aggregated national data.Post-pandemic Brazil experienced a significant rise in hotline reports of VAW but no statistically significant increase in femicide rates. These findings highlight the need for enhanced post-pandemic surveillance, community-based prevention strategies, and primary care interventions to address the growing burden of gender-based violence.