{"id":20545,"date":"2026-07-31T10:33:01","date_gmt":"2026-07-31T10:33:01","guid":{"rendered":"https:\/\/woncaeurope2026.org\/sessions\/my-baby-smells-like-fish-trimetylaminuria-a-case-report\/"},"modified":"2026-07-31T10:33:01","modified_gmt":"2026-07-31T10:33:01","slug":"my-baby-smells-like-fish-trimetylaminuria-a-case-report","status":"publish","type":"wsa_session","link":"https:\/\/woncaeurope2026.org\/fr\/sessions\/my-baby-smells-like-fish-trimetylaminuria-a-case-report\/","title":{"rendered":"My baby smells like fish \u2013 trimetylaminuria: a case report"},"content":{"rendered":"<p>Trimethylaminuria, also known as fish-odor syndrome, is a rare metabolic disorder\u00a0characterized by the inability to convert trimethylamine, a strongly odorous compound,\u00a0into its odorless derivative, trimethylamine N-oxide. The accumulation of trimethylamine in the body leads to a strong fish-like odor. Although clinically benign, the disorder has\u00a0a significant psychosocial impact, affecting self-esteem, social interactions, and overall\u00a0quality of life.This case describes the assessment of a female infant presenting to primary care with\u00a0a recurrent fish-like body odor noticed shortly after the introduction of fish at 7 months of age. The evaluation included clinical history, physical examination, dietary trials\u00a0conducted at home under medical guidance, and referral to a specialized Metabolic Diseases Clinic. The purpose was to clarify the cause of the odor and its\u00a0reproducibility. A multidisciplinary approach involving primary care, nutrition and\u00a0medical genetics allowed structured observation of symptom resolution with dietary\u00a0avoidance and recurrence with reintroduction. Genetic analysis\u00a0confirmed\u00a0FMO3\u00a0deficiency, which encodes the enzyme flavin-containing\u00a0monooxygenase 3. Measurable outcomes consisted of complete symptom remission\u00a0after dietary modification and successful implementation of a long-term management\u00a0plan.Unlike most reported cases, which are diagnosed later in childhood or adulthood, this\u00a0case highlights an unusually early clinical suspicion and confirms the value of primary\u00a0care in recognizing subtle signs of trimethylaminuria, that is rarely described in the\u00a0literature.This case emphasizes the importance of early clinical suspicion and dietary evaluation\u00a0in infants with unexplained body odor. The role of Family Medicine is also important to\u00a0manage psychosocial impact of this condition within the family and community throughout life.This case illustrates the diagnostic challenge of trimethylaminuria in infancy,\u00a0particularly when symptoms are subtle and triggered by early dietary changes. It\u00a0reinforces the need to consider metabolic causes in atypical body odor and highlights\u00a0the value of coordinated care in achieving timely diagnosis.This case emphasizes the importance of early clinical suspicion and dietary evaluation\u00a0in infants with unexplained body odor, encouraging greater awareness in primary care\u00a0and supporting earlier referral pathways to improve long-term management.<\/p>\n","protected":false},"template":"","class_list":["post-20545","wsa_session","type-wsa_session","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/woncaeurope2026.org\/fr\/wp-json\/wp\/v2\/wsa_session\/20545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/woncaeurope2026.org\/fr\/wp-json\/wp\/v2\/wsa_session"}],"about":[{"href":"https:\/\/woncaeurope2026.org\/fr\/wp-json\/wp\/v2\/types\/wsa_session"}],"wp:attachment":[{"href":"https:\/\/woncaeurope2026.org\/fr\/wp-json\/wp\/v2\/media?parent=20545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}