Within the Netherlands, we are performing a national collaborative project (2024-2027) to enhance the collaboration between the seven existing Practice-Based Research Network (PBRN) and the Dutch College of General Practitioners. A PBRN is a collaboration of primary care clinics and clinicians working with researchers to ask and answer real-world questions; essentially acting as "clinical labs" for primary care research. In recent years, regional primary care organizations have become increasingly active and visible. In this project, we explore how the former PBRNs can best collaborate with these more regionally organized stakeholders to gather more aggregated research questions from clinical practice.Within this workshop, we will reflect on our lesson's learned thus far and we hope to inspire and learn from other countries to execute comparable national innovation projects.In the first 30 minutes we will take along the participants through our experiences and results thus far in this national collaboration project. We will present and focus on three main topics: Governance, Data infrastructure and Knowledge Dissemination (10 min each with a different presenter). After 30 minutes, attendees may choose which topic fits their interest most, and within these three smaller groups, we perform, for 30 min, short exercises and share ideas, tips and trics. Attendees receive a small booklet as a thank you and to keep in touch.Attendees will learn the following; Governance: How to develop a national governance model with a clear coordination point to foster collaboration between the regional primary care networks. Data Infrastructure: How to create an integrate and standardized data infrastructure, including a central point for registering and prioritizing research and practice-based questions. Knowledge Dissemination: How to establish a national platform for knowledge exchange, where practice-based questions are consolidated, and interprofessional collaboration is promoted through optimized evaluation tools and regional knowledge sharing.Attendees will be enriched with knowledge on how information is collected from the regions and aggregated at the national level, how this can be assessed, evaluated, discussed, and then returned to the regions. This applies, for example, to tools, working methods, and more formal matters such as contracts and agreements.

The topic is particularly relevant in France, where, in 2025, under the auspices of the Ministry of Health, a working group was established to define a national policy for supporting and developing primary care research (PCR).  The European General Practice Research Network published an important document entitled "Research Strategy for General Practice in Europe 2021." This work updates a previous  one from 2009. The strategy proposes four general objectives : • define research priorities in general practice/family medicine ; • strengthen research capacity ; • develop and promote high standards in research practice ; • facilitate the knowledge transfer from research to clinical practice. The strategy is intended to serve as a basis for developing specific plans in each country, taking into account its characteristics, its specific needs, and its initial level of research capacity. The impact of the strategy can be measured in terms of: • capacity building ; • scientific productivity (dissemination of research results) ; • establishment of networks and collaborations • involvement of stakeholders, policymakers, and the public ; • improved health of citizens.- To identify what has been done in the countries of the workshop participants, and at what level (macro, meso, micro). - To identify obstacles, levers and success factors.Participants will exchange ideas in small groups on PCR policies in their respective countries. Have the general objectives outlined above been translated into operational objectives and action plans ? If so, what is known about their impact? What barriers to the development of PCR have been identified? How have they been, or not, overcome? Following the presentations from the small groups, internationally recognized experts will present an overview of the European situation, and  examples of successful national PCR policies.At the end of the workshop, participants will be able to initiate a dynamic for developing a policy to support PCR, tailored to the needs of their country, and in partnership with other stakeholders.In all European countries, healthcare systems face significant challenges. Finding solutions requires the development of primary care research policies based on internationally shared analysis of successes and failures.

Across Europe, the development of health data warehouses has accelerated to support research, quality improvement, and health system performance, notably in the context of secondary use of health data and cross-border interoperability. However, worldwild primary care (PC) data remain fragmented despite their role in population health. Internationally, PC data networks such as the Canadian CPCSSN and the UK CPRD have demonstrated the value of routinely collected PC data for learning health systems. In France, no national infrastructure previously aggregated routine general practice data. The Plateforme de Données en Soins Primaires (P4DP) was launched to address this gap through a publicly governed, secure, and interoperable PC data warehouse.To describe the governance model, technical architecture, and stakeholder engagement strategy of P4DP and report early implementation milestones and initial analytic outputs.We conducted a descriptive mixed-methods study of the design and early implementation of P4DP. Governance was analysed through document review and stakeholder mapping involving general practitioners, patient partners, researchers, and authorities. PC data were extracted from EHR  and related systems, transformed using standardised terminologies, and stored in a secure cloud infrastructure compliant with GDPR. Interoperability relied on common data principles and standards. International collaborations informed governance and data quality frameworks.a multi-stakeholder steering committee was operational, with active patient partner involvement. The technical infrastructure was deployed, EHR connectors developed, and first data ingestion completed, including prescription data from more than 10,000 patients across pilot sites. Initial outputs included prototype dashboards addressing  practice-level feedback.Early findings highlight that integrating PC into national and European health data ecosystems is feasible but requires governance models adapted to community-based practice, strong professional engagement, and alignment with international interoperability standards. Compared with international networks, P4DP illustrates how publicly governed infrastructures can emerge within the European regulatory context and contribute to globally connected learning health systems.The P4DP early implementation demonstrates the feasibility of a national PC datawarehouse aligned with European and global health data ambitions. These results provide transferable lessons for countries seeking to strengthen PC research capacity and support internationally interoperable learning health systems.

Recruitment remains a major challenge in primary care clinical research, where traditional practice-based identification often results in slow enrolment and delayed study timelines. Direct-to-patient strategies are increasingly recognised as effective alternatives that broaden reach and reduce burden on primary care sites. RiSolve, a prospective remote study evaluating a prescription digital therapeutic for overactive bladder (OAB) in women, implemented a combined traditional and digital recruitment approach across XXX.To evaluate the feasibility, speed, and effectiveness of a direct-to-patient, multi-channel recruitment strategy for enrolling women with bothersome OAB symptoms into a fully remote primary care study.RiSolve is a prospective, single-arm, fully remote study including women (≥18 years) with bothersome OAB symptoms. Recruitment combined paid Meta social-media advertising, Google search visibility, direct-mailing GP practices through the HRB Primary Care Clinical Trials Network XXX (PC-CTNI), in-practice posters and leaflets, liaison with two urogynaecology units, advertisement in local pharmacies and snowball advertising. Interested individuals were directed to review online participant information and study team contact details. Weekly metrics captured expressions of interest, invitations issued, responses, screenings, and consents. Descriptive analysis summarised recruitment volume and engagement patterns.Over 5 weeks, 208 expressions of interest were received, 204 (98%) via social media, with three from in-practice posters and one via GP referral. Sixty potential participants were screened, and 47 were enrolled (ages 43-78, median age 61). The mean recruitment rate was 9.4 participants per week, indicating a rapid enrolment pace for an interventional primary care study in XXX using a direct-to-patient approach. Recruitment increased steadily over the 5-week period, indicating strong public engagement with targeted digital outreach.Direct-to-patient engagement substantially reduced reliance on GP-led identification and facilitated rapid enrolment. Social-media advertising was the primary driver of participation, demonstrating public receptivity to digitally delivered recruitment for women’s health research.The RiSolve study shows that rapid and efficient recruitment into a primary care digital-therapeutics trial is achievable using a direct-to-patient, social-media-enabled strategy. These findings support the feasibility of decentralised recruitment approaches in primary care trials, although further work is needed to confirm sample representativeness.

Recruitment remains a major challenge in primary care clinical research, where traditional practice-based identification often results in slow enrolment and delayed study timelines. Direct-to-patient strategies are increasingly recognised as effective alternatives that broaden reach and reduce burden on primary care sites. RiSolve, a prospective remote study evaluating a prescription digital therapeutic for overactive bladder (OAB) in women, implemented a combined traditional and digital recruitment approach across XXX.To evaluate the feasibility, speed, and effectiveness of a direct-to-patient, multi-channel recruitment strategy for enrolling women with bothersome OAB symptoms into a fully remote primary care study.RiSolve is a prospective, single-arm, fully remote study including women (≥18 years) with bothersome OAB symptoms. Recruitment combined paid Meta social-media advertising, Google search visibility, direct-mailing GP practices through the HRB Primary Care Clinical Trials Network XXX (PC-CTNI), in-practice posters and leaflets, liaison with two urogynaecology units, advertisement in local pharmacies and snowball advertising. Interested individuals were directed to review online participant information and study team contact details. Weekly metrics captured expressions of interest, invitations issued, responses, screenings, and consents. Descriptive analysis summarised recruitment volume and engagement patterns.Over 5 weeks, 208 expressions of interest were received, 204 (98%) via social media, with three from in-practice posters and one via GP referral. Sixty potential participants were screened, and 47 were enrolled (ages 43-78, median age 61). The mean recruitment rate was 9.4 participants per week, indicating a rapid enrolment pace for an interventional primary care study in XXX using a direct-to-patient approach. Recruitment increased steadily over the 5-week period, indicating strong public engagement with targeted digital outreach.Direct-to-patient engagement substantially reduced reliance on GP-led identification and facilitated rapid enrolment. Social-media advertising was the primary driver of participation, demonstrating public receptivity to digitally delivered recruitment for women’s health research.The RiSolve study shows that rapid and efficient recruitment into a primary care digital-therapeutics trial is achievable using a direct-to-patient, social-media-enabled strategy. These findings support the feasibility of decentralised recruitment approaches in primary care trials, although further work is needed to confirm sample representativeness.

Clinical audits are widely utilized in general practice, varying from small-scale initiatives within individual clinics to comprehensive efforts embedded in research and quality improvement programs. Audits enable practitioners to reflect critically on their actions and identify opportunities for improvement and can also provide data for real life research. Audits’ potential as a collaborative approach bridging clinical practice and research remains underexplored.Session discussions will be introduced by brief presentations of audit projects in UK and Denmark general practice. In the UK, the Primary care Academic CollaboraTive (PACT) has built a network of over 1000 clinicians, delivering audit projects at scale which provide participants with benchmarked data for quality improvement while contributing to national research. The PACT project (‘Why Test’ study) collected data from >2,500 patients with recent blood tests in primary care. From Denmark, we will present two in-depth audits of patient trajectories: atrial fibrillation without anticoagulants and suspected familial hypercholesterolemia in high-risk hypercholesterolemia. These examples illustrate diverse methodologies, clinician-driven or researcher-led, and provide a foundation for participants to discuss scope, versatility, and early impact of collaborative audit approaches.Different approaches will be explored and shared, including successess and challenges of creating a network of more than 1000 Primary Care staff who receive personalised feedback and contribute to national priorities and how a data-driven approach can be utilised.This interactive workshop aims to initiate dialogue on strategies to engage general practitioners beyond traditional academic environments in collaborative audit projects to inform a broader research agenda. The session concludes with an open discussion, encouraging participants to share experiences and insights for potential future collaborations. Participants will gain insights into the dual role of clinical audits, enhancing quality improvement in clinical practice and contributing meaningfully to general practice research.Clinical audit and quality improvement, delivered through collobortative networks can be hugely powerful in creating effective and sustainable change in General Practice.