Although periodic health examinations (PHEs) are among the most common reasons for encounter in developed countries, reflecting both patient demand and the role of prevention in general practice, the value of PHEs remains a matter of debate. Evidence indicates that many preventive interventions offer limited benefit and may even cause harm. On the other hand, patients frequently ask for extensive testing during PHEs. This mismatch between limited evidence and patient expectations is a challenge for the doctor-patient relationship and may contribute to overuse of low-value interventions and underuse of evidence-based interventions (evidence–performance gap) with clinical, public health and ethical implications.This workshop aims to (1) update participants on evidence-based recommendations of preventive interventions in a PHE setting; (2) share real-world experiences with PHEs in general practice; (3) identify barriers and enablers to closing the evidence–performance gap in preventive care using PHEs as low-threshold access for best clinical practice, and (4) discuss potential solutions and present a selection of fact sheets for patients, as an example of how to deal with patient expectations.Teaching method: The session will combine brief evidence-based lectures using electronic voting for instant audience feedback, small-group discussions to explore practice variations, and a moderated plenary to synthesize strategies for aligning patient expectations with evidence-based recommendations. Workshop schedule: We will start with an evidence overview of the topic (15 minutes), followed by interactively sharing participants’ experiences (15 minutes). In the second half of the workshop, best practice approaches based on barriers and enablers will be developed co-creatively (20 minutes) and a hands-on tool will be presented (10 minutes), followed by a final take home messageParticipants will be encouraged to reflect on their own consultation patterns and to co-create practical approaches to more effective, personalized, and sustainable preventive care in the setting of PHEs and beyond.The workshop provides evidence, experience sharing, debating and developing a best-practice approach for preventive interventions in the setting of PHEs in general practice.